DNA test – LPPN3 (Laryngeal paralysis and polyneuropathy)

The DNA test for LPPN3 can be used by breeders and owners to screen their dogs for the gene variant linked to this health condition.

What is LPPN3?

LPPN3 (Laryngeal paralysis and polyneuropathy) is an inherited condition that can affect a dog's nerves, causing problems with swallowing, breathing and walking.

Symptoms of LPNN3

Affected dogs may have difficulty breathing, make strange noises when breathing (noisy breathing, wheezing or sounding hoarse when barking), have problems swallowing (gagging) or find it difficult to walk (high stepping, finding it difficult to walk in a straight line or tripping over).

Dogs in some breeds may be affected at a young age (2-3 years old), while others may be affected later on in life.

What causes LPPN3?

LPPN3 is an inherited condition. This means that some dogs may be more at risk of a health issue because of the genes they inherited from their parents. This particular disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from their mother and one from their father) before their health is affected.

Which laboratories we record and publish the results from?

To find out which laboratories The Kennel Club is able to record results from, and which laboratories will send results directly to The Kennel Club, please refer to our website.

Please be aware, The Kennel Club has a set of criteria that we request DNA testing laboratories to meet to enable us to record their results, helping to maintain and protect the integrity of results that appear on a dog’s record. We strongly advise that customers ensure their chosen laboratory is included on our list if they wish The Kennel Club to record and publish the results. Results from laboratories not included on this list will not be recorded.

Breeding advice and what your dog's results mean

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The health test results finder allows you to find the results of DNA tests carried out as part of our official DNA testing schemes for any dog on The Kennel Club’s Breed Register.