The Kennel Club has approved a new official DNA test reporting scheme for early onset progressive retinal atrophy following consultation with the breed’s health co-ordinator on behalf of the breed clubs. Results will be recorded with the abbreviation EOPRA.
Progressive retinal atrophy is a condition that causes the parts of the eye that are sensitive to light to break down. PRA produces a gradual loss of vision in both eyes, eventually leading to total blindness. There are a number of different versions of PRA, but most of them tend to affect older dogs. Early onset PRA, as the name suggests, affects younger dogs, usually around the age of two to three years old.
A number of breeds are affected by PRA, however while the clinical effects are usually similar, the disease can be caused by a number of different genetic mutations. This test examines one of the mutations causing EOPRA in Portuguese Water Dog. Sadly, there is no cure for PRA.
The disease is described as autosomal-recessive. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected.
Tested dogs will be recorded on The Kennel Club systems as either:
Clear
The dog does not have any copies of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected and will only pass on a normal copy of the gene to a puppy.
Carrier
The dog has one copy of the normal gene and one copy of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected, but may pass one copy of the normal gene, or one copy of the abnormal gene on to a puppy.
Affected
The dog has two copies of the abnormal gene associated with the disease. The dog will likely be clinically affected by the disorder and will pass one copy of the abnormal gene on to any potential offspring.
To find out which laboratories The Kennel Club is able to record results from for this test, and which labs will send results direct to The Kennel Club. Find out more about EOPRA.
Please note that these listings are not necessarily comprehensive and other labs may offer the tests. To find out which DNA tests are relevant to your breed, visit our Breeds A-Z.
The Kennel Club constantly reviews DNA testing schemes in conjunction with breed clubs to ensure that breeders are supported with resources which help them to make responsible breeding decisions. The Kennel Club works alongside breed clubs and breed health coordinators in a collaborative effort to improve the health of pedigree dogs and is happy to consider a club's request to add a new DNA test to its lists. A formal request from the breed's health coordinator or a majority request from the breed clubs is normally required to do this.
Test results will be added to the dog’s registration details which will trigger the publication of the result in the next available Breed Records Supplement and also on the Health Test Results Finder on The Kennel Club website.
Results for dogs already tested can also be recorded, but owners will need to submit copies of the DNA certificates themselves. DNA test certificates should be scanned and emailed to Health results (The Kennel Club) .
Owners are reminded that since August 2018, it is mandatory that the dog’s microchip (or tattoo) is recorded along with either the dog’s registered name or registered number on any DNA certificates. Any test results issued after that date that do not carry these identifying features will not be accepted.
Progressive retinal atrophy is a condition that causes the parts of the eye that are sensitive to light to break down. PRA produces a gradual loss of vision in both eyes, eventually leading to total blindness. There are a number of different versions of PRA, but most of them tend to affect older dogs. Early onset PRA, as the name suggests, affects younger dogs, usually around the age of two to three years old.
A number of breeds are affected by PRA, however while the clinical effects are usually similar, the disease can be caused by a number of different genetic mutations. This test examines one of the mutations causing EOPRA in Portuguese Water Dog. Sadly, there is no cure for PRA.
The disease is described as autosomal-recessive. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected.
Tested dogs will be recorded on The Kennel Club systems as either:
Clear
The dog does not have any copies of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected and will only pass on a normal copy of the gene to a puppy.
Carrier
The dog has one copy of the normal gene and one copy of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected, but may pass one copy of the normal gene, or one copy of the abnormal gene on to a puppy.
Affected
The dog has two copies of the abnormal gene associated with the disease. The dog will likely be clinically affected by the disorder and will pass one copy of the abnormal gene on to any potential offspring.
To find out which laboratories The Kennel Club is able to record results from for this test, and which labs will send results direct to The Kennel Club. Find out more about EOPRA.
Please note that these listings are not necessarily comprehensive and other labs may offer the tests. To find out which DNA tests are relevant to your breed, visit our Breeds A-Z.
The Kennel Club constantly reviews DNA testing schemes in conjunction with breed clubs to ensure that breeders are supported with resources which help them to make responsible breeding decisions. The Kennel Club works alongside breed clubs and breed health coordinators in a collaborative effort to improve the health of pedigree dogs and is happy to consider a club's request to add a new DNA test to its lists. A formal request from the breed's health coordinator or a majority request from the breed clubs is normally required to do this.
Test results will be added to the dog’s registration details which will trigger the publication of the result in the next available Breed Records Supplement and also on the Health Test Results Finder on The Kennel Club website.
Results for dogs already tested can also be recorded, but owners will need to submit copies of the DNA certificates themselves. DNA test certificates should be scanned and emailed to Health results (The Kennel Club) .
Owners are reminded that since August 2018, it is mandatory that the dog’s microchip (or tattoo) is recorded along with either the dog’s registered name or registered number on any DNA certificates. Any test results issued after that date that do not carry these identifying features will not be accepted.